Did you know that the Carolina Digital Repository contains information about coronaviruses? Get access to all these resources in the UNC-Chapel Hill Coronavirus Research Collection.

Dissertations, Masters Papers and Masters Theses

• Models of Coronavirus Pathogenesis and Immunity (embargoed by request of author until 12/31/2021) by Anne Elizabeth Beall (2020).
• Effect of Respiratory Viral Panel Testing on Antibiotic Use and Antimicrobial Resistance in Adults: A systematic review of randomized controlled trials and prospective cohort studies by Will Woodhouse (2018)
• Characterizing the Biochemical Determinants Governing MERS-Coronavirus Host Range by Kayla Peck (2016)
• The Impact of the MERS Outbreak in Daily Lives: Sentiment Analysis of Korean Tweets using Time-series Methods by Yongsu An (2016)
• SARS Coronavirus Antagonizes Innate Immune Signaling Initiated by RIG-I but is Recognized by TLR Signaling Via the Adaptor Molecule TRIF by Allison Totura (2014)
• Evaluations Of Severe Acute Respiratory Syndrome Coronavirus Therapeutics And A Viral Capacity For Plasticity And Escape by Meagan Elise Bolles (2013)
• SARS Coronavirus Pathogenesis and Therapeutic Treatment Design by Timothy Patrick Sheahan (2008)
• Computational and Molecular Biology Approaches to Viral Replication and Pathogenesis by Eric F. Donaldson (2008)
• Survival and transmission of coronaviruses in the healthcare environment by Lisa Marie Casanova (2008)
• Inactivation of Surrogate Coronaviruses on Hard Surfaces by Healthcare Germicides by Rachel Hulkower (2008)
• Genetic approaches to the study of coronavirus replication and pathogenesis by Damon Joshua Deming (2007)
• A Partnership for Global Health: Expanding Curriculum and Research in Global Health at the University of North Carolina at Chapel Hill by Gretchen L. Van Vliet (2006).
• Effectiveness of Personal Protective Equipment and Isolation Precautions in Protecting Healthcare Workers from Acquiring Severe Acute Respiratory Syndrome by Robert A. Nyquist (2005)
• Severe Acute Respiratory Syndrome (SARS): A Global Impact by Wanda B. Smith (2004)

Scholarly Articles

2021

• Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo by A. Schäfer et al. (2021). Journal of Experimental Medicine.

2020

• Animal models for COVID-19 (embargoed by publisher until 1/31/2021) by C. Muñoz-Fontela et al. (2020). Nature.
• Broad neutralization of SARS-related viruses by human monoclonal antibodies by Anna Wec et al. (2020). Science.
• Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy (embargoed by publisher until 12/10/2021) by Carlos Cruz-Teran et al. (2020). Advanced Drug Delivery Reviews.
• Characteristics and Outcomes of IBD Patients with COVID-19 on Tofacitinib Therapy in the SECURE-IBD Registry (embargoed by publisher until 12/16/2021) by Manasi Agrawal et al. (2020). Inflammatory Bowel Diseases.
• Coagulation Abnormalities and Thrombosis in Patients Infected with SARS-CoV-2 and Other Pandemic Viruses by N. MacKman et al. (2020). Arteriosclerosis, Thrombosis and Vascular Biology.
• Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV by Timothy P. Sheahan et al (2020). Nature Communications.
• Consensus summary report for CEPI/BC March 12–13, 2020 meeting: Assessment of risk of disease enhancement with COVID-19 vaccines by Paul-Henri Lambert et al (2020). Vaccine.
• The continued epidemic threat of SARS-CoV-2 and implications for the future of global public health by Timothy P. Sheahan and Matthew B. Frieman (2020). Current Opinion in Virology.
• Convalescent Plasma Therapy in Four Critically Ill Pediatric Patients With Coronavirus Disease 2019: A Case Series by Stephanie P. Schwartz et al. (2020). Critical Care Explorations.
• COVID-19 and Inflammatory Bowel Disease: Lessons Learned, Practical Recommendations, and Unanswered Questions by Ryan Ungaro et al (2020). Gastroenterology.
• COVID-19 and mass incarceration: a call for urgent action by A. Macmadu et al. (2020) The Lancet Public Health.
• COVID-19 and Paediatric Inflammatory Bowel Diseases: Global Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto group of ESPGHAN by D. Turner et al. (2020). Journal of Pediatric Gastroenterology and Nutrition.
• COVID-19 cases and testing in 53 prison systems by K. Lemasters et al. (2020). Health and Justice.
• COVID-19: From epidemiology to treatment by J.M. Pericas et al. (2020). European Heart Journal.
• COVID-19 in People with Diabetes: Urgently Needed Lessons from Early Reports by M.C. Riddle et al. (2020). Diabetes Care.
• The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses by Longping V. Tse et al (2020). Frontiers in Microbiology.
• De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2 by Thomas W. Linsky (2020). Science.
• Determining risk factors for mortality in liver transplant patients with COVID-19 by G.J. Webb et al. (2020). The Lancet Gastroenterology and Hepatology.
• Developing guidelines for COVID-19 management: A moving target. An invited commentary on “Evidence based management guideline for the COVID-19 pandemic – Review article” by J. Gallaher and A. Charles (2020). International Journal of Surgery.
• Development and Implementation of a COVID-19 Respiratory Diagnostic Center by Barzin, Wohl and Daaleman (2020). The Annals of Family Medicine.
• Diabetes and COVID-19: Risks, management, and learnings from other national disasters by J. Hartmann-Boyce et al. (2020). Diabetes Care.
• DNA vaccine protection against SARS-CoV-2 in rhesus macaques by J. Yu et al. (2020). Science.
• Do not violate the International Health Regulations during the COVID-19 outbreak by R. Habibi et al. (2020). The Lancet.
• Early impact of COVID-19 on individuals with self-reported eating disorders: A survey of ~1,000 individuals in the United States and the Netherlands by J.D. Termorshuizen et al. (2020). International Journal of Eating Disorders.
• Effect of IBD medications on COVID-19 outcomes: results from an international registry by R.C. Ungaro et al. (2020). Gut.
• Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2 by A.C. Walls (2020). Cell.
• Emergence of a Highly Fit SARS-CoV-2 Variant (embargoed by publisher until 06/30/2021) by Ralph S. Baric. (2020). New England Journal of Medicine.
• Estimation Without Representation: Early Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Studies and the Path Forward by Bonnie Shook-Sal, Ross Boyce and Allison Aiello. (2020). Journal of Infectious Diseases.
• Evaluation of Cloth Masks and Modified Procedure Masks as Personal Protective Equipment for the Public During the COVID-19 Pandemic (embargoed by publisher until 12/10/2021) by P.W. Clapp et al. (2020). JAMA Internal Medicine.
• Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates by K.S. Corbett et al. (2020). New England Journal of Medicine.
• Facilitating Access to a COVID-19 Vaccine through Global Health Law by L.O. Gostin, S.A. Karim and B.M. Meier. (2020). The Journal of Law, Medicine and Ethics.
• Filtration Efficiency of Hospital Face Mask Alternatives Available for Use during the COVID-19 Pandemic (embargoed by publisher until 4/11/2021) by E.E. Sickbert-Bennett et al. (2020). JAMA Internal Medicine.
• Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid (embargoed by publisher until 12/26/2021) by C. Iserman et al (2020). Molecular Cell.
• Guidance for Restarting Inflammatory Bowel Disease Therapy in Patients Who Withheld Immunosuppressant Medications During COVID-19 (embargoed by publisher until 10/31/2021) by C.A. Siegel et al. (2020). Journal of Crohn’s and Colitis.
• Has Global Health Law Risen to Meet the COVID-19 Challenge? Revisiting the International Health Regulations to Prepare for Future Threats by L.O. Gostin, R. Habibi and B.M. Meier. (2020). The Journal of Law, Medicine and Ethics.
• Health and human rights are inextricably linked in the COVID-19 response by S. Sekalala et al. (2020). BMJ Global Health.
• High-Density Amplicon Sequencing Identifies Community Spread and Ongoing Evolution of SARS-CoV-2 in the Southern United States by R.P. McNamara et al. (2020). Cell Reports.
• High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models by Wei Li et al. (2020). Cell.
• A highly immunogenic and effective measles virus-based Th1-biased COVID-19 vaccine (embargoed by publisher until 06/22/2021) by C. Horner et al. (2020). New England Journal of Medicine.
• Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction (embargoed by publisher until 12/3/2021) by H. Katsura et al (2020). Cell Stem Cell.
• Immune Predictors of Mortality After Ribonucleic Acid Virus Infection (embargoed by publisher until 3/1/2021) by Jessica B. Graham. Journal of Infectious Diseases.
• Individuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships by Barry Popkin et al. (2020). Obesity Reviews.
• Inpatient Transition to Virtual Care During COVID-19 Pandemic by M.S. Jones et al. (2020). Diabetes Technology and Therapeutics.
• An invited commentary on “Impact of the Coronavirus (COVID-19) pandemic on surgical practice-part 1”. Impact of the Coronavirus (COVID-19) pandemic on surgical practice: Time to embrace telehealth in surgery by L.N. Purcell and A. Charles. (2020). International Journal of Surgery.
• An Invited Commentary on “World Health Organization declares global emergency: A review of the 2019 novel Coronavirus (COVID-19)”: Emergency or new reality? by L.N. Purcell and A. Charles. (2020). International Journal of Surgery.
• Learning from LMICs: best practices for leveraging sentinel surveillance systems to track the US COVID-19 pandemic by Heather Root, Ross Boyce and Whitney Robinson. (2020). BMJ Global Health.
• Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19 by S.K. Lai, M.D. Sweeney and R.J. Pickles. (2020). Journal of Controlled Release.
• Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting by D.T. Rubin et al. (2020). Gastroenterology.
• A Mechanism‐based Pharmacokinetic Model of Remdesivir Leveraging Interspecies Scaling to Simulate COVID‐19 Treatment in Humans by Patrick Hanafin et al. (2020). CPT: Pharmacometrics and Systems Pharmacology.
• MOUD Provision in Correctional Settings During Time of COVID-19 : Prevention and Solutions (embargoed by publisher until 12/31/2021) by N. Zaller and L. Brinkley-Rubenstein (2020). Journal of Addiction Medicine.
• A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures (embargoed by publisher until 4/13/2021) by K.H. Dinnon III et al (2020). Nature.
• A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice by S.R. Leist et al. (2020). Cell.
• A newcastle disease virus (NDV) expressing a membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine. by W. Sun et al. (2020). Vaccine.
• Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate by W. Sun et al (2020). EBioMedcine.
• No credible evidence supporting claims of the laboratory engineering of SARS-CoV-2 by Shan-Lu Liu et al. (2020). Emerging Microbes and Infections.
• An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice by Timothy P. Sheahan et al (2020). Science Translational Medicine.
• Overview: Systemic Inflammatory Response Derived From Lung Injury Caused by SARS-CoV-2 Infection Explains Severe Outcomes in COVID-19 by R.B. Polidoro et al. (2020). Frontiers in Immunology.
• Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2 by Ren-Di Jiang (2020). Cell.
• Populist Nationalism Threatens Health and Human Rights in the COVID-19 Response by C.R. Williams, J.G. Kestenbaum and B.M. Meier (2020). American Journal of Public Health.
• Possibility for reverse zoonotic transmission of SARS-CoV-2 to free-ranging wildlife: A case study of bats by Kevin J. Olival et al. (2020). PLoS Pathogens.
• Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold by Zehua Sun et al. (2020). mAbs.
• Potently neutralizing and protective human antibodies against SARS-CoV-2 by Seth Jost et al. (2020). Nature.
• Progenitor identification and SARS-CoV-2 infection in human distal lung organoids (embargoed by publisher until 5/25/2021) by Ameen A. Salahudeen et al. (2020). Nature.
• Public health measures to slow community spread of COVID-19 by Benjamin Cowling and Allison Aiello (2020). The Journal of Infectious Diseases.
• Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection by Wei Li et al. (2020). Proceedings of the National Academy of Sciences.
• Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein by S.J. Jost et al. (2020). Nature Medicine.
• The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients by Lakshmanane Premkumar et al. (2020). Science Immunology.
• Reimagining Global Health Governance in the Age of COVID-19 by Lawrence O. Gostin, Suerie Moon and Benjamin Mason Meier (2020). American Journal of Public Health.
• Remdesivir and COVID-19 by Jessie K. Edwards, Stephen R. Cole, and Adaora A. Adimora. (2020). The Lancet.
• Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice by Andrea J. Pruijssers et al. (2020). Cell Reports.
• Return of the Coronavirus: 2019-nCoV by Lisa Gralinski and Vineet D. Menachery. (2020). Viruses.
• The right to health must guide responses to COVID-19 by D. Puras et al. (2020). The Lancet.
• Safety and immunogenicity of SARS-CoV-2 mRNA-1273 vaccine in older adults (embargoed by publisher until 6/17/2021) by E.J. Anderson et al. (2020). New England Journal of Medicine.
• SARS-CoV-2: Combating Coronavirus Emergence by Rachel Graham and Ralph Baric (2020). Immunity.
• SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo by Yixuan J. Hou et al. (2020). Science.
• SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness  by K.S. Corbett et al. (2020). Nature.
• A SARS-CoV-2 protein interaction map reveals targets for drug repurposing by David E. Gordon et al. (2020). Nature.
• SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract by Yixuan J. Hou et al (2020). Cell.
• Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2 by N.E. Ingraham et al. (2020). Critical Care.
• A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2 by A.O. Hassan et al. (2020). Cell.
• Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques (embargoed by publisher until 1/31/2021) by N.B. Mercado et al. (2020). Nature.
• Solidarity in the wake of COVID-19: reimagining the International Health Regulations by A.L. Taylor et al. (2020). The Lancet.
• Survival-Convolution Models for Predicting COVID-19 Cases and Assessing Effects of Mitigation Strategies by Qinxia Wang et al. (2020). Frontiers in Public Health.
• Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection by Caitlin E. Edwards et al. (2020). Proceedings of the National Academy of Sciences.
• A tale of two studies: Study design and our understanding of SARS-CoV-2 seroprevalence (embargoed by publisher until 12/18/2021) by Ross Boyce, Bonnie Shook-Sa and Allison Aiello. (2020). Clinical Infectious Diseases.
• Transmission of viral pathogens in a social network of university students: the eX-FLU study by P.N. Zivich et al. (2020). Epidemiology and Infection.
• Travel restrictions violate international law by B.M. Meier, R. Habibi and Y.T. Yang. (2020). Science.
• Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection by Vineet D. Menachery et al (2020). Journal of Virology.
• Unemployment Insurance, Health-Related Social Needs, Health Care Access, and Mental Health During the COVID-19 Pandemic (embargoed by publisher until 11/30/2021) by Seth Berkowitz and Sanjay Basu (2020). JAMA Internal Medicine.
• Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection (embargoed by publisher until 12/11/2021) by Cole Batty et al. (2020). Advanced Drug Delivery Reviews.
• Validation of the Pandemic Emotional Impact Scale by Sarah Ballou, Sarah Gray and Olafur Palsson (2020). Brain, Behavior and Immunity – Health.
• Working Together to Meet the Needs of Patients With Inflammatory Bowel Diseases by E.J. Brenner and M.D. Kappelman. (2020). Clinical Gastroenterology and Hepatology.

2019

• Antagonism of dsRNA-induced innate immune pathways by NS4a and NS4b accessory proteins during MERS coronavirus infection by Courtney Comar et al. (2019). mBio.
• Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase by Ariane J. Brown et al. (2019). Antiviral Research.
• Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis by Sarah R. Leist et al (2019). PLoS One.
• Practical guidance for clinical microbiology laboratories: Viruses causing acute respiratory tract infections by Carmen L. Charlton et al (2019). Clinical Microbiology Reviews.
• Small-Molecule Antiviral β-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance by Maria L. Agostini et al (2019). Journal of Virology.

2018

• Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease by Madeline G. Douglas (2018). Virology.
• The endonucleolytic RNA cleavage function of nsp1 of middle east respiratory syndrome coronavirus promotes the production of infectious virus particles in specific human cell lines by Keisuke Nakagawa et al. (2018). Journal of Virology.
• Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform by Rachel Graham et al (2018). Communications Biology.
• Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines by Vineet D. Menachery et al (2018). Journal of Virology.
• Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis by Lisa Gralinski et al (2018). mBio.
• Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease by Maria L. Agostini et al (2018). mBio.
• Human coronaviruses and other respiratory infections in young adults on a university campus: Prevalence, symptoms, and shedding by Brian M. Davis et al (2018). Influenza and Other Respiratory Viruses.
• The human sodium iodide symporter as a reporter gene for studying Middle East respiratory syndrome coronavirus pathogenesis by Svetlana Chefer et al (2018). mSphere.
• Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics? by Timothy P. Sheahan and Ralph S. Baric (2018). Future Virology.
• Lysosomal Proteases Are a Determinant of Coronavirus Tropism by Yuan Zheng et al (2018). Journal of Virology.
• MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape by Vineet D. Menachery et al (2018). Proceedings of the National Academy of Sciences of the United States of America.
• Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice by Adam S. Cockrell et al (2018). Mammalian Genome.
• Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro by Jin Soo Shin et al. (2018). Viruses.
• SARS-Like coronavirus WIV1-CoV does not replicate in Egyptian fruit bats (Rousettus aegyptiacus) by Neeltje van Doremalen et al (2018). Viruses.
• A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques by Adam S. Cockrell et al. (2018) Scientific Reports.
• Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses by Bryan Johnson, Rachel Graham and Vineet Menachery (2018). Virology.

2017

• Allelic Variation in the Toll-Like Receptor Adaptor Protein by Lisa Gralinski et al. (2017). G3 – Genes, Genomes, Genetics.
• Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses by Timothy Sheahan et al. (2017). Science Translational Medicine.
• Epigenetic landscape during coronavirus infection by Alexandra Schäfer and Ralph Baric (2017). Pathogens.
• Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus by S.J. Anthony et al. (2017). mBio.
• Jumping species—a mechanism for coronavirus persistence and survival by Vineet D. Menachery et al. (2017). Current Opinion in Virology.
• MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis by Vineet D. Menachery et al. (2017). mBio.
• Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis by Vineet D. Menachery et al. (2017). mSphere.
• Permissivity of Dipeptidyl Peptidase 4 Orthologs to Middle East Respiratory Syndrome Coronavirus Is Governed by Glycosylation and Other Complex Determinants by Kayla Peck et. al. (2017). Journal of Virology.

2016

• 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012 by Reed Johnson et al. (2016). Virology.
• Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses by Jincun Zhao et al. (2016). Immunity.
• Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A by Anne Beall et al. (2016). mBio.
• An effective DNA vaccine platform for Middle East respiratory syndrome coronavirus by Adam S. Cockrell and Ralph S. Baric (2016). Annals of Translational Medicine.
• The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus by Jason E. McDermott et al. (2016). BMC Systems Biology.
• Emerging infectious diseases: Focus on infection control issues for novel coronaviruses (Severe Acute Respiratory Syndrome-CoV and Middle East Respiratory Syndrome-CoV), hemorrhagic fever viruses (Lassa and Ebola), and highly pathogenic avian influenza viruses, A(H5N1) and A(H7N9) by David J. Weber et al (2016). American Journal of Infection Control.
• Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation by Joshua Thornbrough et al. (2016). mBio.
• MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses by Ernesto Nakayasu et al. (2016). mSystems
• A mouse model for MERS coronavirus-induced acute respiratory distress syndrome by Adam Cockrell et al. (2016). Nature Microbiology.
• SARS-like WIV1-CoV poised for human emergence by by Vineet D. Menachery et al. (2016). Proceedings of the National Academy of Sciences of the United States of America.
• Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination by J.A. Otter et al (2016). Journal of Hospital Infection.
• A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses by Lindsey Moser et al. (2016). mSystems.

2015

• Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross by Lisa Gralinski et al. (2015). PLoS Genetics.
• Glycosylation of Mouse DPP4 Plays a Role in Inhibiting Middle East Respiratory Syndrome Coronavirus Infection by Kayla Peck et al (2015). Journal of Virology.
• Human Coronavirus HKU1 Spike Protein Uses O -Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme by Xingchuan Huang et al. (2015). Journal of Virology.
• Molecular pathology of emerging coronavirus infections by Lisa Gralinski and Ralph Baric (2015). The Journal of Pathology.
• New Metrics for Evaluating Viral Respiratory Pathogenesis by Vineet D. Menachery et al. (2015). PLoS ONE.
• The nsp1, nsp13, and M Proteins Contribute to the Hepatotropism of Murine Coronavirus JHM.WU by Rong Zhang et al (2015). Journal of Virology.
• Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus by Davide Corti et al. (2015). Proceedings of the National Academy of Sciences of the United States of America.
• Reply to “Statins may decrease the Fatality Rate of MERS Infection” by Allison L. Totura and Ralph S. Baric (2015). mBio.
• A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence by Vineet D. Menachery et al. (2015). Nature Medicine.
• Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection by Allison L. Totura (2015). mBio.
• Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus by Yang Yang et al (2015). Journal of Virology.

2014

• Attenuation and Restoration of Severe Acute Respiratory Syndrome Coronavirus Mutant Lacking 2′-O-Methyltransferase Activity by Vineet D. Menachery et al. (2014). Journal of Virology.
• A Chimeric Virus-Mouse Model System for Evaluating the Function and Inhibition of Papain-Like Proteases of Emerging Coronaviruses by Xufeng Deng et al. (2014). Journal of Virology.
• Coronavirus non-structural protein 16: Evasion, attenuation, and possible treatments by Vineet D. Menachery et al. (2014). Virus Research.
• Coronavirus Replicase-Reporter Fusions Provide Quantitative Analysis of Replication and Replication Complex Formation by Megan Culler Freeman et al. (2014). Journal of Virology.
• Effects of Human Anti-Spike Protein Receptor Binding Domain Antibodies on Severe Acute Respiratory Syndrome Coronavirus Neutralization Escape and Fitness by Jianhua Sui et al. (2014). Journal of Virology.
• Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates by Christian Selinger et al. (2014). BMC Genomics.
• Evaluation of Serologic and Antigenic Relationships Between Middle Eastern Respiratory Syndrome Coronavirus and Other Coronaviruses to Develop Vaccine Platforms for the Rapid Response to Emerging Coronaviruses by Sudhakar Agnihothram et al. (2014). The Journal of Infectious Diseases.
• Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution by Xian-Chun Tang et al. (2014). Proceedings of the National Academy of Sciences of the United States of America.
• Mouse Dipeptidyl Peptidase 4 Is Not a Functional Receptor for Middle East Respiratory Syndrome Coronavirus Infection by Adam S. Cockrell et al. (2014). Journal of Virology.
• A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant by Sudhakar Agnihothram et al. (2014). mBio.
• A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses by Hugh Mitchell et al. (2014). PLoS One.
• Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses by Vineet D. Menachery. (2014). mBio.
• Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus by Yang Yang. (2014). Proceedings of the National Academy of Sciences of the United States of America.
• The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity by Krystal Matthews et al (2014). Virology Journal.
• Systems approaches to coronavirus pathogenesis by Alexandra Schafer, Ralph Baric and Martin T. Ferris. (2014). Current Opinion in Virology.

2013

• Altering SARS Coronavirus Frameshift Efficiency Affects Genomic and Subgenomic RNA Production by Ewan Plant et al. (2013). Viruses.
• Bugs in the System by Vineet Menachery and Ralph Baric. (2013). Immunological Reviews.
• Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus by Laurence Josset et al. (2013). mBio.
• Crystal Structure of the Receptor-Binding Domain from Newly Emerged Middle East Respiratory Syndrome Coronavirus by Yaoqing Chen et al (2013). Journal of Virology.
• A decade after SARS: strategies for controlling emerging coronaviruses by Rachel Graham et al. (2013). Nature Reviews Microbiology.
• Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury by Lisa Gralinski et al. (2013). mBio.
• Release of Severe Acute Respiratory Syndrome Coronavirus Nuclear Import Block Enhances Host Transcription in Human Lung Cells by Amy C. Sims et al. (2013). Journal of Virology.
• Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus by Trevor Scobey et al. (2013). Proceedings of the National Academy of Sciences of the United States of America.
• RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus by Daniella Ishimaru et al. (2013). Nucleic Acids Research.
• Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures by Renee W.Y. Chan et al. (2013). Journal of Virology.

2012

• Correction: SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b by Bhavna Varshney et al. (2012). PLoS One.
• Emerging human coronaviruses – Disease potential and preparedness by Larry J. Anderson and Ralph S. Baric (2012). New England Journal of Medicine.
• Evidence Supporting a Zoonotic Origin of Human Coronavirus Strain NL63 by Jeremy Huynh et al. (2012). Journal of Virology.
• Increased Antibody Affinity Confers Broad In Vitro Protection against Escape Mutants of Severe Acute Respiratory Syndrome Coronavirus by Mridula Rani et al. (2012). Journal of Virology.
• A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease by Rachel Graham et al. (2012). Nature Medicine.
• Molecular Determinants of Severe Acute Respiratory Syndrome Coronavirus Pathogenesis and Virulence in Young and Aged Mouse Models of Human Disease by Matthew Frieman et al. (2012). Journal of Virology.

2011

• Comparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus Macaques by Barry Rockx et al. (2011). PLoS One.
• Coronaviruses: An RNA proofreading machine regulates replication fidelity and diversity by Mark Denison et al. (2011). RNA Biology.
• A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge by Meagan Bolles et al. (2011). Journal of Virology.
• SARS-CoV and emergent coronaviruses: viral determinants of interspecies transmission by Meagan Bolles et al. (2011). Current Opinion in Virology.
• Successful Vaccination Strategies That Protect Aged Mice from Lethal Challenge from Influenza Virus and Heterologous Severe Acute Respiratory Syndrome Coronavirus by Timothy Sheahan et al. (2011). Journal of Virology.
• Yeast Based Small Molecule Screen for Inhibitors of SARS-CoV by Matthew Frieman et al. (2011). PLoS One.

2010

• Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures by Krzysztof Pyrc et al. (2010). Journal of Virology.
• Effects of Air Temperature and Relative Humidity on Coronavirus Survival on Surfaces by Lisa M. Casanova et al. (2010). Applied and Environmental Microbiology.
• Escape from Human Monoclonal Antibody Neutralization Affects In Vitro and In Vivo Fitness of Severe Acute Respiratory Syndrome Coronavirus by Barry Rockx et al. (2010). The Journal of Infectious Diseases.
• Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing by Lance Eckerle et al. (2010). PLoS Pathogens.
• The Open Reading Frame 3a Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Promotes Membrane Rearrangement and Cell Death by Eric Freund et al. (2010). Journal of Virology.
• Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission by Rachel Graham and Ralph Baric (2010). Journal of Virology.
• The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent by Aartjan J.W. te Velthuis et al. (2010). Nucleic Acids Research.
• SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism by Matthew Frieman et al. (2010). PLoS Pathogens.
• Small molecule inhibitors of the SARS-CoV Nsp15 endoribonuclease by J Ortiz-Alcantara et al (2010). Virus Adaption and Treatment.
• Transcriptomic Analysis Reveals a Mechanism for a Prefibrotic Phenotype in STAT1 Knockout Mice during Severe Acute Respiratory Syndrome Coronavirus Infection by Gregory Zornetzer et al. (2010). Journal of Virology.
• Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture by Aartjan J.W. te Velthuis et al (2010). PLoS Pathogens.

2009

• Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection by Barry Rockx et al. (2009). Journal of Virology.
• Human airway epithelial cell culture to identify new respiratory viruses: Coronavirus NL63 as a model by Bridget Banach et al. (2009). Journal of Virological Methods.
• mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein by Hsaing-I Liao et al. (2009). The Journal of Biological Chemistry.
• A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo by Craig Day et al. (2009). Virology.
• Severe Acute Respiratory Syndrome Coronavirus nsp9 Dimerization Is Essential for Efficient Viral Growth by Zachary Miknis et al. (2009). Journal of Virology.
• Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF- B Signaling by Matthew Frieman et al. (2009). Journal of Virology.

2008

• Animal models and vaccines for SARS-CoV infection by Anjeanette Roberts et al. (2008). Virus Research.
• A Live Attenuated Severe Acute Respiratory Syndrome Coronavirus Is Immunogenic and Efficacious in Golden Syrian Hamsters by Elaine Lamirande et al. (2008). Journal of Virology.
• Mechanisms of Zoonotic Severe Acute Respiratory Syndrome Coronavirus Host Range Expansion in Human Airway Epithelium by Timothy Sheahan et al. (2008). Journal of Virology.
• MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV by Timothy Sheahan et al. (2008). PLoS Pathogens.
• Pathways of Cross-Species Transmission of Synthetically Reconstructed Zoonotic Severe Acute Respiratory Syndrome Coronavirus by Timothy Sheahan et al. (2008). Journal of Virology.
• Persistent Replication of Severe Acute Respiratory Syndrome Coronavirus in Human Tubular Kidney Cells Selects for Adaptive Mutations in the Membrane Protein by Filippo Paccarini (2008). Journal of Virology.
• SARS coronavirus and innate immunity by Matthew Frieman et al. (2008). Virus Research.
• SARS coronavirus replicase proteins in pathogenesis by Rachel Graham et al. (2008). Virus Research.
• SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium by Amy C. Sims et al. (2008). Virus Research.
• Social support and response to AIDS and severe acute respiratory syndrome by A. Nandi et al. (2008). Emerging Infectious Diseases.
• Structural Basis for Potent Cross-Neutralizing Human Monoclonal Antibody Protection against Lethal Human and Zoonotic Severe Acute Respiratory Syndrome Coronavirus Challenge by Barry Rockx (2008). Journal of Virology.
• Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice by Michelle M. Becker et al. (2008). Proceedings of the National Academy of Sciences of the United States of America.
• Systematic Assembly of a Full-Length Infectious Clone of Human Coronavirus NL63 by Eric Donaldson et al. (2008). Journal of Virology.
• Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease by Luis Enjuanes et al. (2008). Virus Research.

2007

• Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeome by Albrecht von Brunn et al. (2007) PLoS One.
• A Mouse-Adapted SARS-Coronavirus Causes Disease and Mortality in BALB/c Mice by Anjeanette Roberts (2007). PLoS Pathogens.
• Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies by Zhongyu Zhu et al. (2007). Proceedings of the National Academy of Sciences of the United States of America.
• Severe Acute Respiratory Syndrome Coronavirus Evades Antiviral Signaling: Role of nsp1 and Rational Design of an Attenuated Strain by Marc Wathelet et al. (2007). Journal of Virology.
• Severe Acute Respiratory Syndrome Coronavirus Open Reading Frame (ORF) 3b, ORF 6, and Nucleocapsid Proteins Function as Interferon Antagonists by Sarah A. Kopecky-Bromberg et al. (2007). Journal of Virology.
• Severe Acute Respiratory Syndrome Coronavirus ORF6 Antagonizes STAT1 Function by Sequestering Nuclear Import Factors on the Rough Endoplasmic Reticulum/Golgi Membrane by Matthew Frieman et al. (2007). Journal of Virology.
• Synthetic Reconstruction of Zoonotic and Early Human Severe Acute Respiratory Syndrome Coronavirus Isolates That Produce Fatal Disease in Aged Mice by Barry Rockx et al. (2007). Journal of Virology.

2006

• Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: Engineering a recombination-resistant genome by Boyd Yount et al. (2006). Proceedings of the National Academy of Sciences of the United States of America.
• Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants by Damon Deming et al (2006). PLoS Medicine.

2005

• The nsp2 Replicase Proteins of Murine Hepatitis Virus and Severe Acute Respiratory Syndrome Coronavirus Are Dispensable for Viral Replication by Rachel Graham et al. (2005). Journal of Virology.
• Humanized mice develop coronavirus respiratory disease by Ralph Baric and Amy Sims (2005). Proceedings of the National Academy of Sciences of the United States of America.
• Severe Acute Respiratory Syndrome Coronavirus Group-Specific Open Reading Frames Encode Nonessential Functions for Replication in Cell Cultures and Mice by Boyd Yount et al. (2005). Journal of Virology.
• Severe Acute Respiratory Syndrome Coronavirus Infection of Human Ciliated Airway Epithelia: Role of Ciliated Cells in Viral Spread in the Conducting Airways of the Lungs by Amy Sims et al. (2005). Journal of Virology.
• Single-Amino-Acid Substitutions in Open Reading Frame (ORF) 1b-nsp14 and ORF 2a Proteins of the Coronavirus Mouse Hepatitis Virus Are Attenuating in Mice by Steven Sperry et al. (2005). Journal of Virology.

2004

• Reverse Genetic Analysis of the Transcription Regulatory Sequence of the Coronavirus Transmissible Gastroenteritis Virus by Kristopher Curtis et al. (2004). Journal of Virology.

2003

• Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus by Boyd Yount et al. (2003). Proceedings of the National Academy of Sciences of the United States of America.

1980-1999

• Episodic evolution mediates interspecies transfer of a murine coronavirus by Ralph Baric et al. (1997). Journal of Virology.
• Interactions between coronavirus nucleocapsid protein and viral RNAs: implications for viral transcription by Ralph Baric et al. (1988). Journal of Virology.
• Specific interaction between coronavirus leader RNA and nucleocapsid protein by Stephen A. Stohlman et al. (1988). Journal of Virology.

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